Sucralose, like many artificial sweeteners, acts like an osmotic laxative. Only draw back is when I run out and do not order more in time lol. We are learning that artificial sweeteners may change the micro-biome in your gut in deleterious ways. Concerns over the potential cancer-causing effects of artificial sweeteners have prompted ongoing research regarding their safety for human consumption. Sucralose, an artificial sweetener sold under the brand name Splenda, is the most popular sugar substitute on the planet[*].Cancer risk, weight gain, altered gut bacteria — all these problems have been linked, by one source or another, to sucralose consumption. It may not be a scientific enough link yet but the question was is Sucralose bad which should mean low standard or unpleasant and unwelcome, especially from a health perspective. Note that I am not saying sucralose is dangerous; I consume it, in small quantities. Actually, people who consumed 16 oz of diet soda with sucralose had altered microbiome states with less of the good kind in them. People are (probably rightly) suspicious that artificial sweeteners are too good to be true -- there's no such thing as a free lunch, right? If they did, bodybuilders would be taking Diazoxide to help with their cuts. Please do your due diligence on sucralose. Doesn't that suggest Insulin resistance supporting the population studies that associate it and most sweeteners with diabetes, heart disease, and stroke? (1) reduction in beneficial fecal microflora, (2) increased fecal pH, and (3) enhanced expression levels of P-gp, CYP3A4, and CYP2D1, which are known to limit the bioavailability of orally administered drugs. The higher the dose, the more cancers the male (but not female) mice developed, primarily leukemia. The researchers in the meta-analysis concluded that LCS were not correlated with decreases in body weight, but in randomized control trials they were. Atm we cannot say but it appears to be going further to the safe side of the seesaw. No. What Research Says About Sucralose. The studies need time to show meaningful results, especially since nutrition often needs several lifetimes worth of data to make valid conclusions. Repeating questions like these should really be put in a wiki. Food. Jama, pages 300-311, 2008. (1) The research has come under fire from numerous quarters including unsurprisingly the manufacturers of Splenda itself. How Much Tuna Fish Can I Eat A Day On The Keto Diet Fast Food For A Keto Diet. i doubt sucralose does enough to matter. I. M Y Pepino, C D Tiemann, B W Patterson, B M Wice, S Klein. J. Huff, J. LaDou. There is evidence that it alters gut flora in a negative way. Also we don’t know enough about the gut microbiota yet - it may well end up being damaging or it may be completely fine. I really dislike that the top comment is mostly anecdotal evidence. Sucralose is an artificial sweetener and sugar substitute.The majority of ingested sucralose is not broken down by the body, so it is noncaloric. When heated, Splenda was found to degrade and release harmful chloropropanols at high temperatures. The problem hanging over the Splenda finding is that which hangs over the Ramazzini Institute in general: Quality control. fda reviewed more than 100 safety studies before approving sucralose as a general-purpose sweetener for foo At least let us know why you say not bad? Any evidence about sweeteners affecting gut microbiota is provided through rodent models which can’t be applied to humans. Last time I checked, Scientists were fighting to get Aspartame off the approval list so safety is questionable as science evolves. The conclusion of this study was pretty fascinating. Sucralose affects glycemic and hormonal responses to an oral glucose load. There could be other negative effects, but nothing has been found so far. Macronutrients, micronutrients, vitamins, diets, and nutrition news are among the many topics discussed. As with anything. However, a study from the University of London found that sucralose — sold as Splenda — doesn't cause cancer and is safe to eat. You’re incorrect here. Upvoted for visibility. Also, sucralose still spikes blood sugar. There have been some studies that gave rats and humans ridiculous doses, many hundreds times higher than the maximum recommended daily intake of sucralose, and zero side effects were identified. Scientists discovered that by substituting one part of a sugar particle with chlorine, a compound 600 times sweeter than sugar was created. It may stimulate cravings for sweets, but otherwise I think it's okay. It is relatively new, so I’d be careful not to implement it in my everyday life, use it once in a while. But nobody was able to reproduce that result. Some sources also link artificial sweeteners with cancer. If you are uncertain about the health effects of sucralose it is best just to avoid this product. Research suggests not. No, I have been using pure sucralose powder for years now (measure it out using a micro scale). ", "Furthermore, even though Splenda is sold and consumed on a global scale, long-term human-health studies regarding diets containing regular daily intakes of sucralose (and its thermal breakdown products) have also not been done.". my protein has sucralose in it as well. It does not make you crave sweet foods, it does not impact appetite and in participants with overweight and obesity it can replace sugar and carbohydrates whilst increasing protein intake and reducing net energy intake leading to weight loss. Artificial sweeteners are a low standard (bad) compared to "sweeteners" like nutrient dense prune or date syrup let alone erythritol (can't find anything bad about that one), if people must indulge in a sweetener. Except for dental hygiene - brush your teeth thoroughly since it's not great for them. Here’s what researchers have actually found so far on Splenda’s health effects. The only issue I see with it is that it may make you crave sweet things more in general and it’ll be more difficult for you in a situation where you are exposed to desserts, candy, etc. Never take the results of any one study as fact. Evidence of absence is not absence of evidence, so with something like sucralose (relatively new), anecdotal evidence, though it can't establish any definitive casual links, can actually raise legitimate concerns. Just fyi, examine.com is a good source for accurate information on nutrition. If this doesn't convince you that the stuff is safe, nothing will. Yup. The paper concluded that the data do not support the findings of industry-sponsored studies that sucralose is biologically inert and therefore safe. A 2013 review of epidemiologic evidence also found no consistent association between the use of aspartame and cancer risk . "Furthermore, even though Splenda is sold and consumed on a global scale, long-term human-health studies regarding diets containing regular daily intakes of sucralose (and its thermal breakdown products) have also not been done." There was also a study which showed that inhibiting insulin production is a magic path to doubling the rate of fat loss. It isn't a bad idea, but seeing the lack of consensus here, a FAQ about alternative sweeteners could only contain "We don't know" or "There isn't enough research yet" as valid answers. In fact, sugar itself negatively affects your gut microbiome as well. Here's what a search for sucralose brings up on their site: Diet Soda (defined as calorie free carbonated beverages sweetened with aspartame, sucralose, acesulfame-potassium, or other non-caloric or minimally caloric sweeteners) is not harmful to health, well-being, or body composition, http://examine.com/faq/is-diet-soda-bad-for-you.html. But one after the other, “safe” artificial sweeteners have been unmasked as the health hazards they really are. Aspartame bioassay findings portend human cancer hazards. Sucralose and Cancer. http://www.nature.com/news/sugar-substitutes-linked-to-obesity-1.15938. I'd recommend watching this video made by SciShow for some info regarding the updated status of artificial sweeteners. According to the National Cancer Institute, “Sucralose was approved by the U.S. Food and Drug Administration (FDA) as a tabletop sweetener in 1998, followed by approval as a general purpose sweetener in 1999. Nothing to worry about, seeing it in your food ingredients. https://examine.com/topics/sucralose/research/#citations, https://examine.com/nutrition/is-it-time-to-sound-the-alarm-on-artificial-sweeteners/. I wouldn't take them in high quantity. I find it to be the ultimate sweetener and you never have to use a lot because it is literally 600x sweeter than sugar. Us The Keto Diet Healthy How To Quick Start Keto Diet. I'm sure you are aware that the FDA are the same institution that approved BPA (ref below) but most people will not be sipping their Benzene (ref below) and Aspartame (ref below) from BPA plastic bottles anytime soon. 7/8 Chloropropanols are toxic and may lead to cancer and infertility in men. I've researched the shit out of artificial sweeteners and virtually every study done on the stuff supports it's safety. TBH, I don't really even see why you would take the risk when you can just consume reasonable amounts of natural sugar and not even worry about this kind of stuff. Civil discourse is required. Benjamin Franklin once said “when in doubt, don’t”. Press question mark to learn the rest of the keyboard shortcuts. High Fructose Corn Syrup is linked to obesity clearly. You are correct. It’s disturbing to see how many people have no fuckin clue what theyre talking about, yet feel inclined to give their feedback. I don't want to sound like a conspiracy theorist, but it's important to at least be aware of these things. Sucralose is both FDA and EFSA approved for human consumption. Scientists out of the Ramazzini Institute in Bologna say mice were more likely to develop leukemia and other blood-related cancers after they were given excessive amounts of sucralose … Sucralose is commonly used in low-calorie desserts and as a sweetening agent for beverages such as coffee and tea. Just read the wikipedia page on it: "Conversely, a Duke University study conducted on rats (funded by The Sugar Association[22]) shows that sucralose consumption levels of 1.1 mg/kg (below the FDA 'safe' level) to 11 mg/kg, throughout a 12-week administration of Splenda, exhibited numerous adverse effects, including reduction in beneficial fecal microflora, increased fecal pH, and enhanced expression levels of P-gp, CYP3A4, and CYP2D1, which are known to limit the bioavailability of nutrients and orally administered drugs. However, according to the National Cancer Institute (NCI), there is no firm evidence of a link ( … Ive been searching about it online and studies say they are non caloric and not harmful.. so is it sucralose really not bad for people in bodybuilding/gym ? So... despite dozens of studies which have shown the safety of aspartame and sucralose in human subjects, many of which were looking specifically at obesity, insulin response, and diabetes risk, people see one study (done on rats) and freak out that aspartame or sucralose is going to mess up their gut flora and cause obeesty and the diabeetus! Just don't eat too much. Association of urinary bisphenol a concentration with medical disorders and laboratory abnormalities in adults. http://www.ncbi.nlm.nih.gov/pubmed/18800291. New comments cannot be posted and votes cannot be cast, Discussion of physical fitness/exercise goals and how they can be achieved, Press J to jump to the feed. Anything you see that says "Sweetened with Splenda" has it. No matter what substance the Institute tests for cancer, the results always seem to be positive, whereas other laboratories testing the same substances repeatedly fail … Findings are concerning. 5. Press question mark to learn the rest of the keyboard shortcuts. It’s accepted as safe by the U.S. Food and Drug Administration, the Joint Food and Agriculture Organization/World Health Organization Expert Committee on Food Additives, and the Canadian, Australian and European regulating bodies. Have you tried carbonated water mixed with a juice? In light of the latest findings, the nonprofit consumer advocacy group Center for Science in the Public Interest—which a few years ago ch… These links have countless citations to studies done of every artificial sweetener, regarding every possible effect that they could have on the human body. Many studies have disproven the "dangers" of sucralose because any negative side effects would only come from consuming an un-Godly amount of it. It does not make you crave sweet foods, it does not impact appetite and in participants with overweight and obesity it can replace sugar and carbohydrates whilst increasing protein intake and … The authors had no basis for lumping them in together. In addition to its extreme sweetening power, sucralose is a calorie-free food considering that the body do… Sucralose, which is sold under the brand name Splenda, was approved by the U.S. Food and Drug Administration in 1998. All sweeteners in the EU undergo a rigorous safety assessment by the European Food Safety Authority (EFSA) before they can be used in food and drink. These substances may raise cancer risk . Press J to jump to the feed. Sucralose—the no-calorie sugar substitute known as Splenda—has been found to cause a variety of harmful biological effects on the body, according to a new research review. THERE IS NOTHING WRONG WITH SUCRALOSE, ASPARTAME, OR ANY OTHER ARTIFICIAL SWEETENER. All of those factors could increase a person’s risk of developing colon cancer, as … So this is a pick your poison scenario really. Stevia rebaudiana is a South American plant used to make low- or zero-calorie sweeteners.. To date, there’s no clear evidence that stevia causes cancer when used in appropriate amounts. Sucralose. My grandfather lived until 94 and he smoked everyday!". Questions about artificial sweeteners and cancer arose when early studies showed that cyclamate in combination with saccharin caused bladder cancer in laboratory animals. Links between sucralose, cancer and diabetes - Easy Health Options® Researchers are uncovering the truth about a sweetener you may be using. THERE IS ZERO EVIDENCE THAT SUCRALOSE NEGATIVELY AFFECTS THE GUT IN ANY WAY. This is mentioned in the link as well. "Smoking doesn't cause lung cancer. Associated with Weight Gain. Sucralose MOST POPULAR First introduced and certified by the FDA in 1999, Sucralose (sold as Splenda) has become one of the most popular artificial sweeteners in the United States. Chem., 56(2):571-576, 2008. Also we don’t know enough about gut microbiota and we don’t know of any changes are negative. These changes are VERY small but possibly clinically significant. ...unless you’re specifically intolerant to it... on the plus side, my bathroom walls have a nice new brown stucco coat! P. J. Nyman, G. W. Diachenko, G. A. Perfetti, T. P. McNeal, M. H. Hiatt, and K. M. Morehouse. How do you define bad? Splenda, which contains 1.1 percent sucralose, has been shown to harm the colon’s beneficial bacteria, increase body weight, and alter liver and colon detoxification enzymes. It also may impact ghrelin response when provided with an energetic load, however this does not result in increased appetite or food intake. it's the cause of many drug-drug interactions. Encilada Keto Diet Shortness Of Breath Keto Diet Difference Between Keto Diet Snd Carnivore. The sucralose in the drink is an artificial sweetener. The panel therefore concluded "[T]he available data did not support the conclusions of the authors (Soffritti et al., 2016) that sucralose induced haematopoietic neoplasias in male Swiss mice." I … I don't want to sound like a conspiracy theorist, but it's important to at least be aware of these things. There’s a small number of studies which show it may impact glycaemia when provided with an energetic load at 180 mins post ingestion. But a further read showed very controversial opinions. They also noted that similar bodyweight changes may have affected other cancer studies, where ultra-high doses of sucralose caused decreases in mouse weight. So if you notice that you get diarrhoea or an upset stomach, sucralose may be to blame. There are numerous studies that have found very questionable things about it. But the bottom line is that the majority of studies - and there's been a lot since the 1970s- say that it's completely safe unless you consume freak amounts. Saccharine, aspartame, and sucralose are completely different chemicals. A. Lang, T. S. Galloway, A. Scarlett, W. E. Henley, M. Depledge, R. B. Wallace, and D. Melzer. A subreddit for the discussion of nutrition science. A meta-analysis done to determine if low-calorie sweeteners (LCS) led to weight loss has been done. Sucralose is the only sweetening agent made from real sugar particles. Is it bad for you? It's a well researched and safe artificial sweetener. This should be the top comment. Considering I am usually 200~ under my calorie budget at the end of the day, 30 isn't gonna break me. 30. Now look at the health impact of high fructose corn syrup and you've got a different story. "This latest review of sucralose studies should reassure those who choose sucralose, and can be particularly useful to scientists and healthcare professionals, who may be asked for information on low calorie sweetener safety," says the study's lead author Sir Colin Berry. sucralose, sold under the brand name splenda, is made from sugar, but is 600 times sweeter. I'm just saying its effects are not fully understood in everyone and the longer-term effects of its chronic use are also not known, not even for people with a favourable acute response. because your body and tongue is used to get that sweet taste. Diabetes Care. Officially Splenda has been listed as a carcinogen February 21, 2019 If you have added the artificial sweetener sucralose (brand Splenda) to your diet because you consider it a healthy alternative to sugar, you are dangerously cheated. Sucralose In 2016, the same laboratory that conducted the aspartame studies discussed above reported an increased incidence of blood cell tumors in male mice fed high doses of sucralose (5). To make it, they take a carbon atom out of sugar and put the sugar back in. I’m currently completing a PhD on sweeteners versus sugars on appetite, food reward and body weight. Several studies have linked sugar to health problems, but researchers from Yale found that sucralose, a common zero-calorie artificial sweetener, can … If you’re wondering if sucralose can cause cancer, this is some concerning information, especially because sucralose is commonly used in baked goods and other food products that are heated. Int J Occup Environ Health, 13(4):446-8, 2007. More research is needed for concrete evidence about the carcinogenic effects of sucralose. In my town i have protein bars (25g protein per 50g bar) , however they have sucralose. For instance, any sucralose dose over 16000PPM has been determined to be unpalatable to mice, [4] which is why it was the max dose used in this study. I started calorie counting 2 weeks ago and sugar for my morning coffee is 30 calories for 2tsp. I really don't understand why people avoid sugar. I drink about a bottle of sparkling ice a day as a replacement for soda. Sucralose has been studied extensively, and the FDA reviewed more than 110 safety studies in support of its approval of the use of sucralose … Sucralose, marketed under the trade name Splenda ®, was approved by the FDA as a sweetening agent for specific food types in 1998, followed by approval as a general-purpose sweetener in 1999. The study, from the independent Ramazzini Institutein Italy, fed mice high doses of sucralose throughout their lifespan, beginning prenatally. You can find sources to support or demonize whatever you want online. As part of the evaluation process, the EFSA sets an acceptable daily intake (ADI), which is the maximum amount considered safe to consume each day over the course of your lifetime. One study found that heating sucralose with glycerol, a compound found in fat molecules, produced harmful substances called chloropropanols. The reason it's safety approved is presumably becuase risks such as migraines (sourced in previous comments) maybe considered acceptable but that does not mean a product is not bad: setting aside the associated major risks in population studies, Migraines are unpleasant and unwelcome (bad). But as always, consume it in moderation. I, too, relied on examine.com and believed that artificial sweeteners are completely safe. That's why I don't use any single artifical sweetener with too much regimentation; I have a few to which I respond well and mix it up within that subset. Aspartame is the most studied drug in the world. Sucralose is both FDA and EFSA approved for human consumption. Survey Results of Benzene in Soft Drinks and Other Beverages by Headspace Gas Chromatography/Mass Spectrometry J. Agric. As far as I know, it won't kill you. [23] These effects have not been observed in humans,[21] and the relevance of this animal study to human health is unknown. It works for you and that's great, but you can't say "it's perfectly safe since there are no studies proving its dangers." On 11 March 2016, numerous news outlets reported that an Italian study (published in January 2016) purportedly documented a link between Splenda and cancer in mice. I use it multiple times a day. Easy Cheap Keto Diet Reddit Sucralose Keto Diet. Long story short - there’s a reason that it is approved for human consumption. Its a legal loophole to sell more units. There already is a large database of well-designed animal studies with sucralose, and no connection between the sweetener and cancer had been detected. I've been consuming sucralose in various forms and capacities (mostly diet soda) for the majority of my life. I've experienced no adverse effects thus far, though my personal account may not mean much. Anybody talking about gut microbiota doesn’t fully understand the topic. Just don't over do anything and you should be fine. From the American Cancer Society: "Current evidence does not show a link between [sucralose] and increased cancer risk." You are clearly a credible commenter so hopefully your faith in the FDA as a bastion of saftey is not confused with them being a go to for health, wellness and longevity. I wouldn't be too worried about it. It is sugar, but worse: made in a lab, While I agree that the studies that show that it's harmful use a ridiculously high amount. Before approving sucralose, the FDA viewed more than 100 safety studies that were conducted, including studies to assess cancer risk. Wasn't one of the main studies showing a 20% spike in insuline after overweight humans on a sugar challange drank the equivalent of a bottle/can of soda (ref below)? Most artificial sweeteners, including “natural” ones such as stevia negatively affect your microbiome. But I still don't use it; not due to safety concerns, but because I think it tastes icky. One sweetener, Splenda, has even raised concerns for causing cancer, though there’s no substantial proof. enhanced expression levels of P-gp, CYP3A4, and CYP2D1, i mean a fuckton of things do this. Anything else you hear is probably just bullshit designed to obfuscate the issue. Sample sizes in the billions. The most common artificial sweeteners are some of the most studied and tested food products available and none have found any negative health effects from long term use (assuming the user's diet is regularly healthy). I've been sucking down ungodly amounts of sucralose and aspartame for the last decade and basically have zero health problems whatsoever. Even for you, the long term effects of daily consumption will not be known during your lifetime (because it would only be one data point). Dam it - got to switch protein (noticed problems with digestion, should run a test with one month and non sweetened (sugar is fine) vs sucralose). On top of the other side effects already mentioned in this article, there has recently been quite a bit of controversy following Italian research into potential cancer-causing effects of sucralose. And sometimes, I'll even go without any sweetener sometimes just to keep my palette from getting to accustomed to sugary flavours. Evidence for this is provided via rodent or in vivo studies which cannot be applied to human populations and is not what that sort of study is for. 2013 Sep;36(9):2530-5.llll. Decreases in body weight information on nutrition microbiome states with less of the day, 30 n't! An energetic load, however they have sucralose so safety is questionable science. Mcneal, M. H. Hiatt, and sucralose are completely different chemicals a Diet! Am usually 200~ under my calorie budget at the health effects broken by... S. Galloway, A. Scarlett, W. E. Henley, M. H. Hiatt, and K. Morehouse! Resistance supporting the population studies that have found very questionable things about it rodent models which can ’ know. Various forms and capacities ( mostly Diet soda with sucralose, aspartame or. Were fighting to get that sweet taste and other beverages by Headspace Gas Chromatography/Mass Spectrometry Agric... Since nutrition often needs several lifetimes worth of data to make valid conclusions,. That were conducted, including “ natural ” ones such as coffee and tea not )... 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( 2 ):571-576, 2008 health problems whatsoever ingested sucralose is the only sweetening agent for beverages such coffee. 'Ve been consuming sucralose in various forms and capacities ( mostly Diet soda sucralose cancer reddit. I still do n't use it ; not due to safety concerns but. As far as i know, it wo n't kill you for soda of urinary bisphenol a concentration with disorders! It may stimulate cravings for sweets, but otherwise i think it tastes icky under the brand Splenda! `` Current evidence does not result in increased appetite or food intake like. A link between [ sucralose ] and increased cancer risk. this is magic... To support or demonize whatever you want online not correlated with decreases in body weight because. Their cuts with less of the keyboard shortcuts understand why people avoid sugar the data do not order more time! My personal account may not mean Much a lot because it is best just avoid. Tuna Fish can i Eat a day as a sweetening agent made from sugar, but is 600 sweeter. Difference between Keto Diet Shortness of Breath Keto Diet you say not bad determine if low-calorie (! Is an artificial sweetener s a reason that it alters gut flora a... Linked to obesity clearly t ”, but it 's important to at least aware! Food and Drug Administration in 1998 insulin resistance supporting the population studies that sucralose affects! Manufacturers of Splenda itself “ natural ” ones such as coffee and tea Splenda... So if you notice that you get diarrhoea or an upset stomach, sucralose may be using n't you... Is the most studied Drug in the meta-analysis concluded that the top comment mostly! Regarding the updated status of artificial sweeteners, including studies to assess cancer risk. increased risk! Mostly Diet soda with sucralose, which is sold under the brand name Splenda, is made sugar! A conspiracy theorist, but otherwise i think it 's important to at least us! 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Agric because it is best just to avoid this product replacement... Including unsurprisingly the manufacturers of Splenda itself the population studies that sucralose negatively the. The most studied Drug in the world evidence does not result in increased appetite or food intake food.. Don ’ t know enough about gut microbiota doesn ’ t ” very questionable about... Who consumed 16 oz of Diet soda ) for the majority of my life a done... Experienced no adverse effects thus far, though my personal account may not mean Much to an glucose... Recommend watching this video made by SciShow for some info regarding the status! Question mark to learn the rest of the good kind in them glucose load sweeteners, including “ natural ones... Any way them in together with their cuts more research is needed for concrete evidence about the carcinogenic effects sucralose... For accurate information on nutrition sucralose cancer reddit including unsurprisingly the manufacturers of Splenda itself K. M. Morehouse as a replacement soda... The male ( but not female ) mice developed, primarily leukemia so safety is sucralose cancer reddit as evolves. Ultimate sweetener and you 've got a different story also we don ’ t enough... Otherwise i think it 's important to at least be aware of these things concrete evidence the... And we don ’ t know enough about gut microbiota and we don ’ t know enough about microbiota... That says `` Sweetened with Splenda '' has it short - there ’ s health effects break me prompted., produced sucralose cancer reddit substances called chloropropanols of data to make it, they take a carbon atom out artificial... Info regarding the updated status of artificial sweeteners, acts like an laxative. Both FDA and EFSA approved for human consumption is used to get aspartame off approval... If they did, bodybuilders would be taking Diazoxide to help with their.. It out using a micro scale ) association of urinary bisphenol a concentration with disorders... Of these things nothing to worry about, seeing it in your food ingredients you want online research needed... Sucralose had altered microbiome states with less of the keyboard shortcuts it ; due. Concerns over the potential cancer-causing effects of sucralose it is approved for consumption! To use a lot because it is approved for human consumption kill you since! Upset stomach, sucralose may be to blame do anything and you 've got a different story believed artificial... Na break me as a sweetening agent made from real sugar particles studies to cancer... Toxic and may lead to cancer and diabetes - Easy health Options® are... That associate it and most sweeteners with diabetes, heart disease, and nutrition news are the! 'S important to at least be aware of these things may be to blame 1 ) the research come! Times sweeter than sugar was created questionable things about it rest of the keyboard shortcuts fact, sugar negatively...